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当前位置: 首页 > 产品中心 > Salinity > 室内生物技术/天然Ara h 6(NA-AH6-1)/1/NA-AH6-1
商品详细室内生物技术/天然Ara h 6(NA-AH6-1)/1/NA-AH6-1
室内生物技术/天然Ara h 6(NA-AH6-1)/1/NA-AH6-1
室内生物技术/天然Ara h 6(NA-AH6-1)/1/NA-AH6-1
商品编号: NA-AH6-1
品牌: inbio
市场价: ¥12100.00
美元价: 6050.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: Salinity
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Allergen:nAra h 6 (Arachis hypogaea allergen 6), peanut
Unit:250µg
Source: Light roasted peanut flour (Runner cultivar)
Mol. Wt:14.5 kD
Purification:

From delipidated peanut extract by multi-step chromatography. Purity on silver stained SDS-PAGE >95%.

Concentration:See Product Insert.
Formulation:

Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Sterile filtered.

Storage:Store at -20ºC
Notes:

Trace Ara h 1 and Ara h 2 levels <0.05%.

PDB:
Product Resources:Natural Ara h 6 Certificate of Analysis
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
  1. Kleber-Janke T, Crameri R, Appenzeller U, Schlaak M, Becker WM. Selective cloning of peanut allergens, including profilin and 2S albumins, by phage display technology. Int Arch Allergy Immunol 1999; 119: 265-74.
  2. Suhr M, Wicklein D, Lepp U, Becker W. Isolation and characterization of natural Ara h 6: Evidence for a further peanut allergen with putative clinical relevance based on resistance to pepsin digestion and heat. Mol Nutr Food Res 2004; 48: 390-9.
  3. Koppelman S, de Jong G, Laaper-Ertmann M, Peeters K, Knulst A, Hefle S, Knol E. Purification and immunoglobulin E-binding properties of peanut allergen Ara h 6: evidence for cross-reactivity with Ara h 2. Clin Exp Allergy 2005; 35: 490-7.
  4. Peeters KA, Koppelman SJ, van Hoffen E, van der Tas CW, den Hartog Jager CF, Penninks AH, Hefle SL, Bruijnzeel-Koomen CA, Knol EF, Knulst AC. Does skin prick test reactivity to purified allergens correlate with clinical severity of peanut allergy? Clin Exp Allergy. 2007 Jan;37(1):108-15.
  5. Flinterman AE, van Hoffen E, den Hartog Jager CF, Koppelman S, Pasmans SG,Hoekstra MO, Bruijnzeel-Koomen CA, Knulst AC, Knol EF. Children with peanut allergy recognize predominantly Ara h2 and Ara h6, which remains stable over time. Clin Exp Allergy. 2007 Aug;37(8):1221-8.
  6. Porterfield HS, Murray KS, Schlichting DG, Chen X, Hansen KC, Duncan MW, Dreskin SC. Effector activity of peanut allergens: critical role for Ara h 2, Ara h 6, and their variants. Clin Exp Allergy 2009; 39: 1099-108.
  7. Blanc F, Adel-Patient K, Drumare M, E, Wal J, Bernard H. Capacity of purified peanut allergens to induce degranulation in a functional in vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors. Clin Exp Allergy 2009; 39: 1277-85.
  8. Flinterman AE, Pasmans S, den Hartog Jager CF, Hoekstra MO, Bruijnzeel-Koomen C, Knol EF, van Hoffen E. T cell responses to major peanut allergens in children with and without peanut allergy. Clin Exp Allergy 2010; 40: 590-7.
品牌介绍
indoor biotechnologies由前弗吉尼亚大学医学和微生物学教授,UVA哮喘和变态反应中心的成员Martin D. Chapman博士创立。Chapman博士是美国过敏,哮喘和免疫学研究院的院士,并曾担任美国国立卫生研究院,环境保护署,学术机构和《财富》 500强公司的顾问。室内生物技术专业生产抗过敏和哮喘的生物制剂。该公司是评估家庭,工作场所,学校和商业建筑中过敏原环境暴露的全球领导者。该公司生产用于过敏研究和诊断的高纯度过敏原,并在过敏原结构,功能和免疫识别方面的研究获得国际认可。室内生物技术的使命是改善过敏和哮喘患者的生活质量。