| Allergen: | nAra h 1(Arachis hypogaea allergen 1) |
| Unit: | 1mg(supplied as 4 x 0.25mg aliquots) |
| Availability: | 10 business day lead time |
| Source: | Blanched peanut, crushed (Runner cultivar) |
| Mol. Wt: | 64.5 kD (monomer) |
| Purification: | From delipidated peanut extract by affinity chromatography. Purity on silver stained SDS-PAGE >95%. |
| Concentration: | See product insert. |
| Labeling Ratio: | See product insert. |
| Formulation: | Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Sterile filtered. |
| Storage: | (1) Store at -20ºC. (2) Avoid freeze thaw cycles. (3) Protect from exposure to light. |
| Notes: | (1) Upper band is Ara h 1 trimer. (2) Two minor bands below the monomer are Ara h 1 fragments 3. (3) The Biotin Natural Ara h 1 is an InBio™ Product. |
| Product Resources: | BiotinNatural Ara h 1 Certificate of Analysis |
| Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. | |
| References: | |
1. Burks AW, Williams LW, Helm RM, Connaughton C, Cockrell G, O"Brien T. Identification of a major peanut allergen, Ara h 1, in patients with atopic dermatitis and positive peanut challenges. J Allergy Clin Immunol 1991; 88(2):172-9.2. Burks AW, Cockrell G, Stanley JS, Helm RM, Bannon GA. Recombinant peanut allergen Ara h 1 expression and IgE binding in patients with peanut hypersensitivity. J Clin Invest 1995; 96(4):1715-21.3. Maleki SJ, Kopper RA, Shin D, Park CW, Compadre CM, Sampson H, Burks AW, Bannon GA. Structure of the major peanut allergen Ara h 1 may protect IgE-Binding epitopes from degradation. J Immunol 2000; 164:5844-5849.4. Pomés A, Helm RM, Bannon G, Burks AW, Chapman MD. Monitoring peanut allergen in food products by measuring Ara h 1. J Allergy Clin Immunol 2003; 111(3):640-645. | |
